Colt Python 4.25

If you are searching for the Colt Python 4.25, you are looking at the most popular barrel length in the entire Python lineup. When Colt relaunched the Python in 2020, the 4.25-inch model was the first one they brought back — and for good reason. It is the most versatile Python ever made, equally at home on the range, in a home defense setup, or sitting proudly in a collector’s case.

What Is the Colt Python 4.25?

The Colt Python 4.25 is a double-action, .357 Magnum revolver with a 4.25-inch barrel, manufactured by Colt’s Manufacturing Company in Hartford, Connecticut. It holds 6 rounds and can also fire the softer .38 Special round.

The 4.25-inch barrel length was chosen by Colt as the ideal balance point between the compact 3-inch and the longer 6-inch model. It gives you:

• Enough barrel for great accuracy without being too long to handle
• Good velocity from .357 Magnum ammunition
• Balanced weight that is easy to shoot and easy to hold
• Versatility — it works for home defense, range shooting, collecting, and carry

The NRA’s editorial director, Mark Keefe, called the 4.25-inch blued Python “a lovely gun” — and that sums it up perfectly.

Colt Python 4.25 Full Specs

Here are the complete specifications for both the stainless and blued Colt Python 4.25 models currently available in 2025:

Why the 4.25-Inch Barrel Is the Most Popular Python

The Colt Python is available in barrel lengths from 2.5 inches all the way up to 8 inches. So why does the 4.25-inch model outsell them all? The answer is simple: it does everything well.

Perfect Size for Almost Any Use

At 9.75 inches overall and 42 ounces, the Colt Python 4.25 is big enough to feel substantial and stable in your hands, but not so large that it becomes awkward to use. It fits naturally in a holster, sits comfortably on a nightstand, and handles smoothly at the range.

Strong Accuracy Without Extreme Length

The 4.25-inch barrel provides a long enough sight radius to deliver excellent accuracy at common shooting distances — 7 yards, 15 yards, and 25 yards. Field testers have kept six rounds in an inch and a half to two inches standing offhand at 15 yards. That is outstanding performance for a production revolver.

Best All-Around .357 Magnum Performance

The 4.25-inch barrel extracts excellent velocity from .357 Magnum rounds. You get most of the ballistic benefit of the full cartridge without the added length of the 6-inch barrel.

The First Python Back on the Market

When Colt relaunched the Python in 2020, the 4.25-inch stainless model was the launch gun — which tells you exactly what Colt believes is the most important barrel length in the lineup. The gun they chose to represent the Python’s comeback speaks for itself.

Colt Python 4.25: Stainless vs. Blued

The Colt Python 4.25 is available in two distinct finishes, and choosing between them is the biggest decision most buyers face.

Stainless Steel — Model PYTHON-SP4WTS

The stainless Python 4.25 was the original 2020 relaunch model. It has a bright, polished stainless steel finish that is nearly mirror-like in quality.

Key features:

• Stronger, more corrosion-resistant modern stainless alloy (upgraded from the 410-series used in vintage models)
• Near-mirror polished finish
• Walnut grips with Colt medallion
• Requires minimal maintenance

Choose Stainless If You:

• Live in a humid climate (the coast, the South, the Pacific Northwest)
• Shoot it frequently and want easy maintenance
• Prefer a bright, modern look
• Want the most weather-resistant Python available

MSRP: ~$1,499 – $1,599

Blued Carbon Steel — Model PYTHON-BP4WTS

The blued Python 4.25 was introduced in 2024 and has become one of the most requested Python models since the relaunch. It features deep carbon steel bluing with gold medallion walnut grips — a look that echoes the classic Pythons of the 1950s, 60s, and 70s.

The NRA calls it “the one that many Python fans wanted all along” from today’s Colt.

Key features:

• Carbon steel frame with deep blue finish
• Altamont solid walnut grips with gold Colt medallions
• Signature ventilated rib barrel with a third vent on the 4.25-inch model
• Fully adjustable rear sight with red ramp front sight

Choose Blued If You:

• Want the classic, traditional Python appearance
• Are buying it primarily as a collector’s piece
• Want to match the look of the original pre-1999 Pythons
• Don’t mind applying a light oil after handling to maintain the finish

MSRP: ~$1,599 – $1,699

Colt Python 4.25 Performance Review

Trigger Feel

The trigger on the Colt Python 4.25 is what every shooter talks about first. In double-action mode, the pull is measured at 9 lbs 9 oz — but it does not feel heavy because it is smooth and consistent all the way through with zero stacking. This is due to the redesigned U-shaped spring Colt introduced in the 2020 relaunch, which specifically eliminated the stacking (rough increase in pull weight) that some vintage Pythons could develop over time.

In single-action mode, the break comes in at 5 lbs 6 oz — clean, crisp, and predictable with no creep and no overtravel.

Most shooters who pick up the Python 4.25 for the first time say the same thing: they have never felt a production revolver trigger this good.

Accuracy

The Colt Python 4.25 is one of the most accurate production revolvers you can buy. The combination of:

• Tight ~0.006-inch barrel-to-cylinder gap
• 6-groove, 1:14″ left-hand twist rifling
• Recessed target crown protecting the muzzle
• Smooth, consistent trigger pull

…all work together to deliver tight, repeatable groups. Field testing shows the 4.25-inch Python keeping six rounds in 1.5 to 2 inches at 15 yards from a standing unsupported position — which is exceptional for a production handgun.

Recoil

At 42 ounces, the Python 4.25 has enough weight to absorb the recoil of .357 Magnum loads without being punishing to shoot. The full underlug beneath the barrel shifts weight forward of the grip, naturally reducing muzzle flip and helping the gun return to target quickly for follow-up shots.

If you want lighter recoil for practice or range sessions, the Python handles .38 Special rounds smoothly and comfortably.

Build Quality

The modern Python 4.25 uses CNC machining to maintain extremely tight tolerances throughout. The frame has 30% more steel in critical areas — including the top strap and behind the rear sight — compared to the original Python design. Every chamber, barrel throat, and cylinder is precisely machined for consistent performance.

The stainless model uses a stronger, more corrosion-resistant alloy than the 410-series stainless used in vintage Pythons. The blued model uses carbon steel with a deep, even finish that is evenly applied and resistant to the minor abrasions of regular use.

Colt Python 4.25 vs. 6 Inch

This is the most common comparison buyers make. Here is a direct, honest breakdown:

Bottom Line: Choose the 4.25-inch if you want the most versatile Python that works for home defense, everyday range shooting, and general use. Choose the 6-inch if your primary goal is maximum precision, target competition, or handgun hunting and you do not need to carry or maneuver it in tight spaces.

For most buyers, the 4.25-inch is the right answer.

Colt Python 4.25 Price

New Production Prices

Street prices at dealers will vary slightly. Some major retailers run manufacturer rebate promotions that can bring the effective price below MSRP by $100 or more. Always check for current promotions before purchasing.

Used / Pre-Owned Prices (2020 – 2024 Production)

The Python 4.25 holds its value extremely well in the secondary market:

Special & Engraved Editions

Colt has released several limited-edition Python 4.25 models at premium price points:

Who Is the Colt Python 4.25 Best For?

Home Defense: The 4.25-inch barrel is long enough for great accuracy but compact enough to use in the tight spaces of a home. The .357 Magnum cartridge is one of the most powerful and proven self-defense rounds available in a revolver. The smooth double-action trigger means you can fire quickly and accurately without cocking the hammer.

Range Shooters: The Python 4.25 is an absolute pleasure to shoot at the range. The trigger, the balance, and the accuracy all combine to make every trip to the range more enjoyable. The option to shoot .38 Special ammunition makes practice sessions more affordable.

Collectors: The 4.25-inch model was the flagship of the 2020 relaunch, making it historically significant in the Python’s modern era. Special editions and engraved models in this barrel length are especially desirable to collectors.

New Python Buyers: If you are buying your first Colt Python and are not sure which barrel length to start with, the 4.25-inch model is the right choice. It is the most versatile, the most widely available, and the easiest to live with as an everyday shooter and display piece.

Firearms Investors: Like all Python models, the 4.25 holds and grows in value. New Python values have risen over $210 in the past 12 months. Limited editions in the 4.25-inch size are especially strong performers at auction.

Colt Python 4.25 vs. Competitors

The Python costs more than its competition — but it delivers more in trigger quality, craftsmanship, finish quality, and long-term value than either the Smith & Wesson 686 or the Ruger GP100 can match.

Where to Buy the Colt Python 4.25 in the USA

The Colt Python 4.25 is available across the USA through multiple trusted channels:

Authorized Colt Dealers — Find a dealer near you at colt.com using the dealer locator. This is the safest and most reliable way to buy new.

Sportsman’s Warehouse — Carries new stainless and blued Python 4.25 models with occasional manufacturer rebates.

Palmetto State Armory (PSA) — One of the largest online retailers for new Colt Python 4.25 models including the blued Target edition.

GunBroker.com — The largest online gun marketplace. Wide selection of new, used, and vintage Python 4.25 models from thousands of trusted sellers.

Guns.com — New and used inventory with condition grading. Ships to your local FFL dealer.

GunsAmerica.com — Solid marketplace for both new and used Python 4.25 models.

Rock Island Auction Company — For rare, engraved, and vintage Python 4.25 models at live and online auction.

Frequently Asked Questions: Colt Python 4.25

What is the Colt Python 4.25? The Colt Python 4.25 is a double-action .357 Magnum revolver with a 4.25-inch barrel made by Colt’s Manufacturing Company. It is the most popular barrel length in the Python lineup and was the model chosen to lead Colt’s 2020 Python relaunch.

How much does the Colt Python 4.25 cost in 2025? New stainless models retail for approximately $1,499 to $1,599. New blued models retail for $1,599 to $1,699. Used modern models range from $750 to $1,550 depending on condition.

What is the weight of the Colt Python 4.25? The Colt Python 4.25 weighs 42 ounces (2.625 lbs) unloaded. This weight gives the gun excellent balance and helps manage recoil.

What is the overall length of the Colt Python 4.25? The overall length is 9.75 inches, making it a full-size revolver that is compact enough to use in a variety of practical situations.

What caliber is the Colt Python 4.25? It is chambered in .357 Magnum and can also safely fire .38 Special ammunition, which produces less recoil and is more affordable for practice.

Is the Colt Python 4.25 good for home defense? Yes. The 4.25-inch barrel is a great length for home defense — accurate, powerful, and easy to maneuver. The double-action trigger allows fast, reliable firing without needing to cock the hammer.

What is the difference between the stainless and blued Colt Python 4.25? Both models shoot identically. The stainless model (PYTHON-SP4WTS) uses a corrosion-resistant stainless alloy with a bright polished finish. The blued model (PYTHON-BP4WTS) uses carbon steel with a deep blue finish and gold walnut grips for a classic look. Choose stainless for durability, choose blued for traditional aesthetics.

Is the Colt Python 4.25 better than the 6-inch? It depends on what you want to do with it. The 4.25-inch is better for all-around use, home defense, and versatility. The 6-inch is better for target shooting, hunting, and maximum accuracy. For most buyers, the 4.25-inch is the right choice.

Can the Colt Python 4.25 shoot .38 Special? Yes. The Python 4.25 is chambered in .357 Magnum and can safely fire .38 Special ammunition. This makes practice more affordable and reduces recoil for casual range sessions.

Where can I find a Colt Python 4.25 in stock? Check authorized dealers via colt.com, or visit Sportsman’s Warehouse, Palmetto State Armory, GunBroker.com, and Guns.com. Stock availability varies by model and finish — the blued model in particular sees high demand.

Does the Colt Python 4.25 hold its value? Yes — very strongly. The Python is one of the best value-retaining production revolvers in the USA. Used modern models sell for 75 to 95% of original MSRP, and the trend of new prices has risen over $210 in the past 12 months alone.

What grips come on the Colt Python 4.25? Both the stainless and blued models come with Altamont solid walnut target-style grips with the gold Colt rampant horse medallion. The grips are checkered for a secure hold.